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ErgoX™ Ergothioneine

Targeted Super Antioxidant Against Age

Products name: L-Ergothioneine, EGT

CAS No.: 497-30-3

ANTI-AGING
BEAUTY CARE
COGNITION HEALTH
LIVER HEALTH
SLEEP HEALTH
CARDIOVASCULAR HEALTH

About Ergothioneine

Ergothioneine

Ergothioneine is a unique amino acid recognized as the “world’s strongest antioxidant,” for its powerful antioxidant properties. Found naturally in ergot fungi in 1909, ergothioneine accumulates in human tissues such as red blood cells, the liver, and kidneys. However, the human body cannot synthesize it; it must be obtained through diet.

Why Do We Need Ergothioneine?

Ergothioneine plays a crucial role in reducing oxidative stress, a key factor in accelerated aging and chronic diseases. It not only protects cells from oxidative stress damage caused by free radicals outside the cells but can also penetrate inside the cell, particularly into crucial organelles like mitochondria, offering comprehensive protection and significantly slowing the aging process.

Health Benefits of Ergothioneine

ANTI-AGING
BEAUTY CARE
COGNITION HEALTH
LIVER HEALTH
SLEEP HEALTH
CARDIOVASCULAR HEALTH

Unlock ergothioneine potentials

Ergothioneine is a UNIQUE AMINO ACID

Ergothioneine is a SUPER ANTIOXIDANT

EGT Inhibits Lipid Peroxides 5x Better Than CoQ10 [1]
EGT Cleans Free Radicals 3x Faster Than Glutathione [2]

Why ErgoX Ergothioneine

High purity: Purity≥99.5%

Proprietary Enzyme and Fermentation Process: Utilizing advanced cell factory technology, ErgoX™ employs a proprietary enzyme to biosynthesize ergothioneine in a safe, efficient manner, significantly reducing costs.

Excellent Quality: Strictly regulate the content of heavy metals and microorganisms to ensure the product’s safety and high quality.

Better appearance: Pure white powder with uniform particle size and no odor.

Versatile applications: Excellent cold water solubility, stability, and dispersibility, making it easier to incorporate into diverse dietary supplements and cosmetic product formats.

Qualification Assurance

Frequently Asked Questions About ErgoX™ Ergothioneine

01 Why do we need ergothioneine supplements?
Ergothioneine, or l-ergothioneine, is a super antioxidant that can help overall health and cellular well-being. Recent studies show that ergothioneine supplements can contribute to the prevention of a variety of inflammatory and cardiometabolic diseases[3][4], making it a promising ingredient for long-term wellness. In addition, ergothioneine skin benefits are gaining attention in the beauty and personal care industry, as this compound may help protect skin from oxidative damage and support a youthful appearance.
02 Is ergothioneine a vitamin?
Not officially, but it’s under serious consideration. Scientists are exploring the idea of classifying ergothioneine as an essential vitamin due to its strong anti-aging potential. It fits key vitamin criteria: it's obtained only through diet, transported by a dedicated system in the body, and low levels are associated with cognitive decline and chronic diseases. If recognized, it would be the first new vitamin added since B12 in 1948. This potential classification has sparked interest from ergothioneine manufacturers worldwide,
03 How long does it take for ergothioneine supplements to work?
The effects of ergothioneine can vary depending on the individual and the health goal. Continuous intake is very important for long-term health benefits. As a protective antioxidant, it begins accumulating in the body’s tissues soon after supplementation, especially in areas prone to oxidative stress like the brain, liver, and bone marrow. While immediate effects may not be noticeable, consistent use over weeks to months may support long-term benefits such as reduced inflammation, improved cellular protection, and better cognitive and cardiometabolic health.
04 What are the dietary sources of ergothioneine?
Mushrooms are the primary dietary source of ergothioneine, with certain varieties containing notably high concentrations. Additionally, ergothioneine can be found in smaller amounts in other foods such as fermented products (e.g., tempeh, kimchi), grains like oats and barley, and animal-derived foods including liver, kidney, and kidney beans. However, due to limited dietary availability, supplementation is often recommended, especially as the L-ergothioneine market grows in response to rising consumer interest in proactive health and anti-aging solutions.

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Reference available upon request.
The content on this page is for business use only and is not intended for end consumers.

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Information on this site is provided for informational purposes only. It is not meant to substitute for medical advice from your physician or other medical professional. You should not use the information contained herein to diagnose or treat a health problem or disease or prescribe any medication. Carefully read all product documentation. If you have or suspect that you have a medical problem, promptly contact your regular healthcare provider.

ErgoX™ is a trademark of EffePharm Ltd.

Reference

[1] Dong, Kelly K, et al. “A Comparison of the Relative Antioxidant Potency of L‐Ergothioneine and Idebenone.” Journal of Cosmetic Dermatology, vol. 6, no. 3, 24 Aug. 2007, pp. 183–188, https://doi.org/10.1111/j.1473-2165.2007.00330.x. Accessed 23 Apr. 2024.

[2] Franzoni, F., et al. “An in Vitro Study on the Free Radical Scavenging Capacity of Ergothioneine: Comparison with Reduced Glutathione, Uric Acid and Trolox.” Biomedicine & Pharmacotherapy, vol. 60, no. 8, Sept. 2006, pp. 453–457, https://doi.org/10.1016/j.biopha.2006.07.015. Accessed 1 Nov. 2019.

[3] Borodina, Irina, et al. “The Biology of Ergothioneine, an Antioxidant Nutraceutical.” Nutrition Research Reviews, vol. 33, no. 2, 13 Feb. 2020, pp. 190–217, https://doi.org/10.1017/s0954422419000301. Accessed 24 Oct. 2021.

[4] Cheah, Irwin K., and Barry Halliwell. “Ergothioneine, Recent Developments.” Redox Biology, vol. 42, Jan. 2021, p. 101868, https://doi.org/10.1016/j.redox.2021.101868.

Ergothioneine: The Rising Star in Skincare Innovation

With the rise of science-backed skincare, ergothioneine is gaining well-deserved recognition as a promising anti-aging ingredient. Named a “longevity vitamin” due essentially to its outstanding antioxidant and anti-inflammatory effects on human skin, this natural amino acid enables protection of the skin from oxidative stress, an impact to reduces inflammation, and visibly slows the aging process.

According to Effepharm, the leader in ergothioneine production, their L-Ergothioneine, Ergox™, is not just a highly pure product that can seriously take care of your skin’s cells but ergothioneine skin benefits can also substantially fortify the skin barrier with the result of the skin looking not only brighter but also smoother in no time.

The L-ergothioneine market is expanding fast, as consumers become more and more conscious about the products they use and, at the same time, they would like to keep them very effective and clean, definitely propelling the growth of this market which in turn would provide a platform where all innovations happens. It is not debatable that it is highly beneficial to utilize ergothioneine as an active ingredient in product development as it satisfies the needs of health-conscious and results-oriented customers and brands can also gain a leading position by that.

Recent developments show that ergothioneine is no fad but a true game-changer in longevity and cellular protection—especially for brands sourcing it from top ergothioneine manufacturers like Effepharm, who are poised to lead the skincare revolution.

For more information, visit effepharm.com.