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UTHEVER® Cosmetic

β-Nicotinamide Mononucleotide（NMN）

CAS No. :1094-61-7

Product Name: UTHEVER® Cosmetic NMN (β-Nicotinamide Mononucleotide)
Newly Certified Cosmetic Ingredient 2023, with scientifically validated skincare benefits.

 

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    1.7 Times Stronger Anti-Wrinkle Effe8ct

     

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    Whitening Effect

     

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    Prevent Skin UVB Damage

     

  • 6

    Moisturizing Effect

     

  • 4

    Skin repair

     

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    Antioxidant support

     

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About UTHEVER® Cosmetics

β-Nicotinamide Mononucleotide (NMN) is a derivative of vitamin B3, which plays a crucial role in human cell functions. NMN can be naturally produced in cells or obtained through fruits, vegetables, and poultry. Research shows that NMN is a bioactive compound that can boost cellular NAD+ levels. As we age, NAD+ levels in the body decline. Supplementing NAD+ can effectively slow down aging and improve the prevention and management of age-related diseases.

 

More about UTHEVER® NMN

Mechanisms of NMN

  • UTHEVER® NMN

    Increase NAD+ levels

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    Activate "longevity protein" sirtuins

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    Repair DNA damage

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    Promote energy production

Skin Support

 

 

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NMN, Rising Potent Skincare Ingredient

NMN, short for β-Nicotinamide Mononucleotide, has been scientifically proven to rapidly and effectively increase NAD+ levels in the body. The influence of NMN now spread to the skincare field by targeting multiple pathways and dimensions to maintain skin health.

 

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UTHEVER®: Newly Certified Cosmetic Ingredient 2023

In February 2023, the China National Medical Products Administration approved the application of UTHEVER® NMN as a cosmetic ingredient submitted by EffePharm. UTHEVER® NMN can now be officially used as a cosmetic ingredient and the finished product can be legally marketed and sold.

 

Enter the UTHEVER® Scientific Skincare Era

UTHEVER® NMN
As a clinical-backed NMN brand, UTHEVER® Cosmetics’ scientifically validated skincare benefits include:

 

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Repairing Skin Barrier

Human Efficacy Trials

Thirty-one healthy female subjects aged 18 to 60 years, all with dry skin, a compromised skin barrier, and transepidermal water loss exceeding 15 g/m²/h, continuously used Uthever® NMN at a concentration of 3% for 14 and 28 days. The results indicated a reduction in transepidermal water loss of 26.23% and 37.60% respectively, demonstrating that Uthever® NMN possesses significant moisturizing properties.

 

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Hydration Benefits

Human Efficacy Trials

Thirty-one healthy female subjects aged 18 to 60 years, all with dry skin, a compromised skin barrier, and transepidermal water loss exceeding 15 g/m²/h, continuously used Uthever® NMN at a concentration of 3% for 14 and 28 days. The results showed that the hydration level of the stratum corneum increased by 32.44% and 54.66%, respectively, indicating that Uthever® NMN has a significant repair effect.

 

More about our clinical trials agenda
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1.7 Times Stronger Anti-Wrinkle Effect

In a controlled experiment targeting wrinkles, using Uthever® NMN at a concentration of 0.625%, the increase in Type I collagen production was 70% higher compared to Vitamin C and Vitamin E. It effectively activates the repair of damaged cells, eliminates ageing cells, promotes the differentiation and regeneration of healthy cells, and creates youthful, firm, and rejuvenated skin.

 

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Prevent Skin UVB Damage

Photodamage is a significant factor in skin aging, and by increasing intermediate filament-related proteins like FLG and IVL, the skin barrier can be fundamentally repaired. Research has found that NMN effectively enhances the levels of FLG and IVL in the skin, repairing the stratum corneum and countering photodamage caused by UVB exposure. This effect was further demonstrated in a study using orally administered Uthever® NMN in mice.

 

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Brighting Effect

As age increases, the number of free radicals rises, leading to reduced skin vitality, loss of elasticity, formation of wrinkles, overall skin aging, dull complexion, and formation of pigmentation. The experimental results in the following figure demonstrate that Uthever® NMN can effectively eliminate free radicals in the skin, restore firm and elastic skin, improve pigmentation, and give the skin a more radiant glow.

 

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Moisturizing Effect

AQP3 is one of the main indicators for measuring skin hydration. In experiments focused on skin moisturization, immunofluorescence is used to track the quantity of AQP3 (as indicated by IOD values in the image below). Uthever® NMN has been proven to increase the number of skin AQP3 at different concentrations, achieving deep hydration effects.

 

UTHEVER® NMN Skincare Solutions: Elevate Your Market Leadership

We have innovatively combined the cutting-edge anti-aging ingredient NMN with skincare products, utilizing freeze-drying technology to create freeze-dried ampoule serums and masks. These two products harness the synergistic effects of multiple ingredients to penetrate deeply into the skin for intensive repair. Suitable for all ages and skin types, they effectively address a variety of skin concerns while enhancing the skin’s natural radiance.

 

NMN Freeze-Dried Ampoule Serum

Dual Chamber Design: Every Drop Counts!
One serum, multiple benefits.

 

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  • 01 Clinically Backed Patented NMN
    Our formula contains 99.5% high-purity UTHEVER® NMN, validated by independent testing. This powerful ingredient helps repair the skin, provides hydration, protects against free radicals, reduces wrinkles, and firms the skin.
  • 02 Extensively Tested Formula
    Combines ergothioneine and peptides for intensive skin repair, deep hydration, moisture retention, and anti-aging benefits.
  • 03 Fresh Activation Technology
    The dual chamber design keeps powder and liquid separate to prevent degradation. Tear, then push to activate the ingredients.

NMN Ampoule Essence Mask

Dual Chamber Design: Every Drop Counts!

 

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  • 01 Clinically Proven Patented NMN
    Our formula contains 99.5% high-purity UTHEVER® NMN, validated by independent testing. This powerful ingredient helps repair the skin, provides hydration, protects against free radicals, reduces wrinkles, and firms the skin.
  • 02 Powerful Ingredient Blend for Repair
    Features a combination of acetyl hexapeptide-8, hexapeptide-9, soluble collagen, and squalane. Together, these ingredients nourish the skin, lock in moisture, and minimize the appearance of wrinkles.
  • 03 Comfortable Tencel Fiber Mask
    The soft Tencel membrane molds perfectly to your skin while allowing it to breathe. This design helps preserve the active ingredients for maximum effectiveness.
  • 04 Freeze-Dried Freshness for Optimal Results
    Our advanced -40°C vacuum freeze-drying technology keeps the ingredients fresh, ensuring that you receive intense hydration when you apply the mask.

Establish Your Ideal Skincare Line with UTHEVER®'s Formulation Trio

Our high-potency formulas are enriched with pure actives, optimally penetrating the skin to correct signs of aging, protect healthy skin, and prevent future damage, resulting in lasting beauty.

 

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UTHEVER® NMN ACR11 Complex™

Skincare Concerns: Dullness, loss of radiance, uneven skin tone, dark spots.

Description: The ACR11 Complex™ repairs and revitalizes epidermal stem cells, enabling them to function like younger skin cells and banishing dullness at the cellular level. Combined with the dual efficacy of β-NMN+Niacinamide, the ACR11 Complex™ decodes skin’s luminosity and lets the skin regain a glow of radiance.

Fresh Activation Technology
The dual chamber design keeps powder and liquid separate to prevent degradation. Tear, then push to activate the ingredients.

 

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UTHEVER® AST Complex™

Skincare Concerns: Serious lines and wrinkles, lifting, contouring, loss of firmness, tone, boosting natural collagen.

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Step 1: Eliminate free radicals with the super antioxidant 【Ergothioneine】.
Step 2: Promote DNA repair with 【β-NMN】for a rejuvenated glow.
Step 3: Reshape and revitalize skin’s elasticity with 【Retinol】 + 【Saccharomyces Ferment Filtrate】.
Restore. Regenerate. Revive. Enter the 360° “AgeShields” era.

 

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UTHEVER® AST Complex™

Skincare Concerns: Antioxidant protection, visible age prevention, loss of firmness, tone, wrinkles, and dryness.

Description: The AST Complex™ is Uthever®’s patented formulation designed to prevent the first signs of aging.
Step 1: Super antioxidant [Ergothioneine] eliminates free radicals, halting photoaging at its source.
Step 2: [β-NMN] effectively clears aging cells, promoting DNA repair for a rejuvenated glow.
Step 3: [Retinol] + [Saccharomyces Ferment Filtrate] stimulate collagen from the core, reshaping and revitalizing skin’s elasticity.
Restore. Regenerate. Revive. Enter the 360° all-powerful “AgeShields” era.

 

Why Uthever Cosmetics?

 

 

 

 

UTHEVER® NMN

Customer Site

To read more about Uthever® NMN, or would like to find out Uthever® NMN where to buy, visit uthever.com.
If you are a brand formulating with Uthever® NMN and would like to be featured on our site, please contact us.

 

Qualification
Assurance

  • UTHEVER® is an NPA 2023 member brand, strictly adhering to NPA standards at every processing stage. 
  • Kosher and halal certified.
  • Manufactured in IOS9001, and cGMP facilities.
  • Manufacturing according to cGMP standard
  • Halal
  • ISO 9001
  • Kosher

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Reference available upon request.

The content on this page is for business use only and is not intended for end consumers.

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Information on this site is provided for informational purposes only. It is not meant to substitute for medical advice from your physician or other medical professional. You should not use the information contained herein to diagnose or treat a health problem or disease or prescribe any medication. Carefully read all product documentation. If you have or suspect that you have a medical problem, promptly contact your regular healthcare provider.

UTHEVER® is a registered trademark of EffePharm Ltd.

 

 

 

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