2025-08-28 Best Senolytic Supplements in 2025 for Healthy Aging Senolytic supplements target harmful senescent “zombie” cells that accelerate aging and inflammation. Key ingredients such as fisetin, curcumin, quercetin, EGCG, piperlongumine, olive polyphenols, apigenin, and liposomal resveratrol are supported by scientific studies for promoting healthier aging, better energy, and stronger cellular resilience.