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PEA

LipoAvail^® is an advanced liposomal technology that encapsulates PEA within a double molecular layer of lipids, enhancing the bioavailability of PEA.

Compared with regular PEA, the relative bioavailability of LipoAvail^® PEA is elevated by 28 times.

ANTI-INFLAMMATORY
PAIN RELIEF
NERVE SYSTEM SUPPORT
IMMUNE SUPPORT

About PEA

PEA

Palmitoylethanolamide (PEA) is a naturally occurring fatty acid amide that functions as a nuclear factor agonist. Produced by the body in response to inflammation and pain, PEA plays a crucial role in regulating cellular signaling pathways, making it an essential component of the body’s natural defense mechanisms.

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Why LipoAvail™ PEA

Overcoming PEA Absorption Challenges

Conventional PEA (palmitoylethanolamide) is highly lipophilic and nearly insoluble in water, with a solubility of just 4 mg/L, making it hard for the body to absorb when taken orally.^[1] Studies show that most PEA doesn’t enter the bloodstream, resulting in low bioavailability and limiting its potential health benefits.

28 times higher PEA relative bioavailability

Relative bioavailability is the ratio of AUC_0-t for LipoAvail^® PEA and regular PEA after oral administration, indicating the effect of PEA absorption elevated by LipoAvail™ liposomal technology.

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Outstanding Physicochemical Properties

We deliver authentic liposomal PEA under LipoAvail^® 360° multi-dimensional quality evaluation system.

PEA content of 50%, 70%,

Regular spherical morphology,

Excellent particle size distribution with an average diameter of 45 nm.

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Versatile Application

Cold water dispersibility

Regular PEA (as shown on the left) is insoluble in water, with evident stratification.

LipoAvail™ PEA (as shown on the right) can be dispersed evenly in water as an emulsion.

Powder
Tablets
Hard capsules
Softgel capsules

Qualification Assurance

Frequently Asked Question About LipoAvail® Liposomal PEA

01 Are liposomal PEA better than the regular one?
Yes, liposomal PEA (palmitoylethanolamide) supplements offer better absorption and higher efficacy compared to regular ones. Liposomal delivery systems encapsulate PEA in a lipid bilayer, similar to the body’s cell membranes. PEA liposomes exhibit improved absorption into the bloodstream, resulting in enhanced bioavailability and efficacy. According to our lab-tested results, liposomal delivery can significantly increase the relative bioavailability of PEA up to 28 times, making it more effective at lower doses.
02 Are liposomal PEA safe?
Yes, liposomal PEA (palmitoylethanolamide) is generally considered safe when used as directed. PEA is a naturally occurring fatty acid amide found in the body and has been studied for its anti-inflammatory and pain-relief properties. The liposomal form enhances absorption without altering the compound's fundamental safety profile. As with any supplement, it's essential to select a high-quality source that is manufactured under strict quality control. Businesses formulating with liposomal PEA should ensure their supplier provides safety data, purity certificates, and third-party testing to meet regulatory standards.
03 How to choose the best liposomal PEA supplement?
To select the best liposomal PEA supplement, look for products that offer proven bioavailability, high purity, and clear labeling. Check if the manufacturer uses advanced liposomal delivery systems, such as nano-encapsulation or phospholipid-based carriers, to enhance absorption. It’s also essential to verify third-party lab testing for potency and contaminants. For capsule or powder formulations, sourcing from a reputable liposomal PEA manufacturer with GMP certification ensures quality, consistency, and regulatory compliance. B2B buyers should also consider the supplier’s capacity for handling bulk orders, providing custom formulation support, and providing technical documentation.

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Reference available upon request.

The content on this page is for business use only and is not intended for end consumers.

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Information on this site is provided for informational purposes only. It is not meant to substitute for medical advice from your physician or other medical professional. You should not use the information contained herein to diagnose or treat a health problem or disease or prescribe any medication. Carefully read all product documentation. If you have or suspect that you have a medical problem, promptly contact your regular healthcare provider.

LipoAvail^® is a registered trademark of EffePharm Ltd.

Reference:

[1] Clayton, Paul, et al. “Palmitoylethanolamide: A Potential Alternative to Cannabidiol.” Journal of Dietary Supplements, 28 Nov. 2021, pp. 1–26, https://doi.org/10.1080/19390211.2021.2005733.

Your Trusted Liposomal PEA Manufacturer for Superior Absorption and Results

As a leading liposomal PEA manufacturer, EffePharm specializes in delivering high-quality palmitoylethanolamide (PEA) ingredients designed for enhanced bioavailability and superior efficacy. Our advanced liposomal technology ensures better absorption and stability, helping your supplement formulations stand out in a competitive market. Whether you are formulating capsules, powders, or functional products, our PEA liposomal solutions are optimized for next-level performance.

Palmitoylethanolamide Supplements with Proven Bioavailability

Traditional palmitoylethanolamide powder struggles with poor water solubility and low oral bioavailability. That is why we have developed a next-generation palmitoylethanolamide supplement with enhanced efficacy, utilizing our proprietary liposomal delivery system. This innovation allows for more efficient delivery to the bloodstream, ensuring that your end products can deliver real, measurable results to consumers.

Bulk PEA Powder and Custom Formulations Available

We offer palmitoylethanolamide bulk powder in both standard and liposomal forms, making it easy to scale your production while maintaining consistent quality. Our PEA ingredients are ideal for use in a variety of applications, including capsule PEA supplements, sachets, and blends. All our products are manufactured under strict quality standards and are available in bulk quantities for global B2B distribution.

Why Choose Us as Your Liposomal PEA Partner?

With a strong track record in ingredient innovation and large-scale manufacturing, EffePharm is more than just a supplier of palmitoylethanolamide — we are your long-term strategic partner. From technical support to customized formulation services, we provide end-to-end solutions that help you bring high-efficacy PEA products to market faster.